• aa-utp SMAD plays a pivotal role in the

  2018-11-07

  

  SMAD4 plays a pivotal role in the pathological progression of vascular disorder (Zhang et al., 2016). SMAD4, a member of Smad family, is a central mediator in the canonical TGF-β signaling. It regulates biological processes important for the pathogenesis of TAAD, such as SMCs migration and prolifera

• These characteristics of Tat secretion are remarkably overla

  2018-11-07

  

  These characteristics of Tat secretion are remarkably overlapping with those of cellular FGF-2, which is also sensitive to ouabain and involves binding of the factor to the Na+,K+-ATPase (Dahl et al., 2000; Florkiewicz et al., 1998; Smith et al., 2001; Trudel et al., 2000; Zeitler et al., 2015), whi

• br Experimental design materials and methods br Conflicts of

  2018-11-07

  

  Experimental design, materials and methods Conflicts of interest Acknowledgments This study was founded by grants from CNPq (Conselho Nacional do Desenvolvimento Científico e Tecnológico - process 302885/2011-0) and CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). Mirian

• br Acknowledgements br Data The front panel and

  2018-11-07

  

  Acknowledgements Data The front panel and block diagrams constituting the LabVIEW® Virtual Instrument (VI) are shown (Figs. 1–4) to demonstrate the software/programmatic component of the pHstat system. Figs. 1 and 2 depict the front panel of the two functionalities of the VI. The front panel i

• The aim of this study was not

  2018-11-07

  

  The aim of this study was not to directly compare the mentalistic and non-mentalistic accounts for social valence detection described in the introduction, as there are many aspects of neural activity that are not accessible via ERP techniques. We hypothesized a P400 component because both these acco

• On the behavioral level we expected that the pattern of

  2018-11-07

  

  On the behavioral level we expected that the pattern of aggression after positive, neutral, and negative feedback would be similar across the pilot, test and replication samples, with negative feedback resulting in the highest levels of aggressive behavior. On the neural level we examined both the g

• As the third component of the

  2018-11-06

  

  As the third component of the conceptual framework, the design studio is the medium in which cognitive activities occur (Onal, 2010). Interaction between learning and teaching is another factor of these cognitive activities. This interaction supports the awareness and understanding of cognitive acti

• From the point of view of the impact of modernity

  2018-11-06

  

  From the point of view of the impact of modernity, we could conclude that the Xianxian-Daming handbook is rather conservative. On the one hand, the Western authors refused inculturation and any stylistic evolution to a Sino-Christian style. On the other hand, they say nothing about modern techniques

• If a variable speed pump control is applied in Case

  2018-11-06

  

  If a variable-speed pump control is applied in Case 2, then the electricity consumption of the water pumps can be reduced. However, handling a situation where the cooling consumption is extremely low and unevenly distributed among different households is relatively difficult (as Fig. 8 shows). Other

• Introduction Microvascular free flap surgery is one of the m

  2018-11-06

  

  Introduction Microvascular free flap surgery is one of the most important operations in reconstructive surgery especially in dealing with large or complex defects. Because of the advancement of the microsurgical technique, the success rate of free flap pedicle anastomosis is currently >90%. An even

• br Discussion Benign FH is usually of two

  2018-11-06

  

  Discussion Benign FH is usually of two types: cutaneous type and that involving deep soft tissues. Histologically, deep FH has many features in common with cutaneous cellular FH, including a storiform and/or short fascicular growth pattern, similar cytologic features with frequently limited or ab

• Voiding symptoms may influence health care seeking behavior

  2018-11-06

  

  Voiding symptoms may influence health care-seeking behavior through QOL impairment in Japanese men. The QOL score revealed more pronounced differences between men admitted to clinics and entacapone settings than did the IPSS category. The Core Lower Urinary Tract Symptom Score questionnaire is more

• Both CE and AE have recently been included on

  2018-11-06

  

  Both CE and AE have recently been included on the WHO Neglected Tropical disease list. Echinococcosis has a global estimated disease burden of 2–5×107 DALY (Disability Adjusted Life Years) highlighting the considerable medical, social and economic impacts on animal and human populations worldwide (T

• br Conflict of interest br

  2018-11-06

  

  Conflict of interest Acknowledgement Introduction Diabetes mellitus (DM) is a serious global health program which is characterized by high blood glucose levels, which lead to complications such as retinopathy, hypertension, neuropathy and diabetic foot ulcers [1]. Type 2 DM caused by defect

• As this transporter is regulated by redox reaction we invest

  2018-11-06

  

  As this transporter is regulated by redox reaction, we investigated whether there was any change in SVCT2 ambroxol hydrochloride with age. Our study shows that there is an age dependent decrease in SVCT2 transcript number in old mice femur along with other bone marker such as Collagen type 1, BMP-2,

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