• 84 br Functional consequences of ADK regulation on neuronal

  2023-02-20

  

  Functional consequences of ADK regulation on neuronal excitability Adenosine modulates neuronal excitability via activation of the high affinity A1 or A2A, low-affinity A2B, or low abundance A3 adenosine receptors that feed into a multitude of different neuronal and astrocytic pathways (Blum et a

• By promoting bundling and processive elongation of

  2023-02-20

  

  By promoting bundling and processive elongation of peptide yy australia filaments and inhibiting association of capping protein with filament barbed ends, Ena/VASP family proteins contribute to the dynamics of lamellipodia and filopodia [41] and maintenance of focal adhesions and tight junctions [42

• Previous studies have demonstrated that the expression of th

  2023-02-20

  

  Previous studies have demonstrated that the expression of the Aurora B gene is maximally increased at G2/M phage during mitosis (Honda et al., 2003, Fu et al., 2007, Goldenson and Crispino, 2015), and exhibits an extraordinary upregulation in a number of human cancers (Fu et al., 2007, Kollareddy et

• br Materials and methods br Results br Discussion In this

  2023-02-20

  

  Materials and methods Results Discussion In this study, the orphan receptor GPR25 was cloned from several representative vertebrate species including zebrafish. Although the overall amino UNC 0646 sequence identity among these species is not high (38–52%), our synteny analysis clearly indic

• Besides one should also consider that all

  2023-02-20

  

  Besides, one should also consider that all antioxidant compounds (free soluble or insoluble bounds) exist all together in colon, where radicals and antioxidant compounds react continuously with each other. At this point, after the consumption of antioxidants bound to dietary fiber, they reach the c

• The subnuclear localizations of redox regulators is also lar

  2023-02-20

  

  The subnuclear localizations of redox regulators is also largely unknown. The potential role of thiol reductases as transcription regulators or DNA repair molecules may suggest an association to DNA. In this way, the presence of a zinc finger domain potentially involved in protein/DNA interactions o

• Although sex hormones activational effects

  2023-02-20

  

  Although sex hormones (activational effects) are known to directly interact with RAS (Baiardi et al., 2005, Miller et al., 1999, Silbiger and Neugarten, 1995), the potential contribution of organizational hormonal and SCC effects on physiological sex-based difference in the regulation of the RAS rem

• br Conclusions Extract of non germinated winter rape seeds c

  2023-02-20

  

  Conclusions Extract of non-germinated winter rape seeds cv. Bellevue was screened for the aminopeptidase activity. It revealed broad substrate specificity, with the highest activity toward Phe-pNA. Also in the partially purified sample, phenylalanine was preferentially hydrolysed. PMSF, known ser

• br Introduction Several studies have found

  2023-02-20

  

  Introduction Several studies have found that hypothalamic Akt-mediated signaling pathways play critical roles in the regulation of food intake and Tarafenacin metabolism in mammals [[1], [2], [3], [4], [5], [6]]. Central injections of the inhibitor of phosphoinositide 3- kinases (PI3 K, an upstre

• sn-Glycero-3-phosphocholine br Discussion AhR is a receptor

  2023-02-20

  

  Discussion AhR is a receptor that binds to a great variety of lipophilic compounds, in particular those containing at least one aromatic ring (Abel and Haarmann-Stemmann, 2010, Guyot et al., 2013, Hahn, 2002). The main known function of this receptor is to induce the metabolism of these compounds

• Polyphenols like flavonoids have the potential to penetrate

  2023-02-13

  

  Polyphenols like flavonoids have the potential to penetrate into lipid bilayers which is vital for enabling protection against oxidation. Rosmarinic Daptomycin is a natural polyphenol antioxidant isolated from Sphaeranthus amaranthoides. Polyphenols can inhibit the propagation of lipid oxidation by

• Miconazole br Results and discussion br Conclusion

  2023-02-13

  

  Results and discussion Conclusion A series of aminobenzothiazole derivatives were investigated as possible Aurora B kinase inhibitors. Bioisosteric replacement of the heterocyclic core of the lead compound was performed regarding the docking analysis. Replacement of the oxygen Miconazole of t

• There are profound differences between acute and chronic pai

  2023-02-13

  

  There are profound differences between acute and chronic pain when dramatic changes occur in peripheral nociceptors and central nociceptive pathways and the pain system is sensitised thereby leading to exaggerated responses to noxious stimuli (hyperalgesia) and responses to non-noxious stimuli (allo

• br Activity and expression of aromatase in

  2023-02-13

  

  Activity and expression of aromatase in the hippocampus The brain, like the adrenals, gonads and the placenta, is a steroidogenic organ. This paradigm emerged from studies carried out as early as the 1980s by Baulieu and co-workers; these studies showed that steroids such as pregnenolone and dehy

• The AT hook motif is highly conserved in evolution from

  2023-02-13

  

  The AT-hook motif is highly conserved in evolution from bacteria to humans and is found in one or more copies in a large number of other, non-HMGA, proteins, many of which are transcription factors or are involved in chromatin remodeling [8]. For example, AT-hook peptide motifs are essential compone

16443 records 361/1097 page Previous Next First page 上5页 361362363364365 下5页 Last page