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Multiple mechanisms have been described that sensitize ESCs
2018-10-24
Multiple mechanisms have been described that sensitize ESCs to DNA damage-induced apoptosis. First, human ESCs possess unique ROCK-dependent mechanisms in singularized sodium butyrate that lead to a myosin-mediated form of cell blebbing, which rapidly triggers apoptosis upon cell detachment (Ohgush
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br Conclusion The number of colonies at the first isolation
2018-10-24
Conclusion The number of colonies at the first isolation step could only represent a more or less rich ECFC content of the donor but we demonstrated that the initial clonogenicity was also related to distinctive intrinsic stemness, proliferative and functional features. Moreover, our results enab
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Multi electrode array approaches have been proposed as
2018-10-24
Multi-electrode array approaches have been proposed as a tool for detecting functional changes in electrically excitable cells, including neurons, exposed to drugs or toxins and allow use in high throughput studies (McConnell et al., 2012). Although there are a number of electrophysiological measure
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The neurogenic to gliogenic transition of NSPCs is
2018-10-24
The neurogenic-to-gliogenic transition of NSPCs is probably governed by a multi-layered system. The epigenetic status of astrocyte-specific (Takizawa et al., 2001) and neurogenic genes changes during development (Hirabayashi et al., 2009; Kishi et al., 2012; Pereira et al., 2010), critically determi
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br Experimental Procedures br Author Contributions N N G per
2018-10-24
Experimental Procedures Author Contributions N.N.G. performed most of the experimental work, with the help of M.G., J.L., and P.G.P. C.S.J. helped perform in vivo cell transplantation experiments. S.A.M. and F.R. were responsible for inducible Pax7 lineage-tracing experiments. A.A. performed q
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br A derivative of a cut off curve gives
2018-10-24
A derivative of a cut-off curve gives us the Bisindolylmaleimide V Supplier axial energy distribution in the input beam: N(W∥) = –dS/du. According to Eq. (1), there are three ways to calculate the cut-off function from the experimental data: If the analyzer operates properly, these three functi
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Fiber separation in the reinforcing yarns and damages in
2018-10-24
Fiber separation in the reinforcing yarns and damages in the yarn matrix may occur during the deformation of flexible woven composite materials due to debonding between the reinforcing fibers and the adhesive. These processes can be described as \'smeared cracks’ [18-21]. This description is based o
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The acoustic signals produced by dolphins Yana and Yasha wer
2018-10-24
The acoustic signals produced by dolphins Yana (1) and Yasha (2) were recorded with no special training and no food reward for the dolphins. The periods of time used was when the dolphins habitually swam to walkway 5 (located 0.1m above the water level), and remained afloat at the water surface with
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The characteristic points in which sensors were mounted on
2018-10-24
The characteristic points in which sensors were mounted on the sample were chosen based on the results of the preliminary computation. These points are shown in Fig. 1. Experimental procedure Acoustic anisotropy was measured in selected points of the sample before loading; the value equal to +0.
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However this explanation of stress as a direct cause of
2018-10-24
However, this explanation of stress as a direct cause of social disparities in physical health does not account for the fact that socially-disadvantaged groups, particularly African Americans and Hispanics in the US, despite having higher morbidity and mortality, have better mental health relative t
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Community capacity building eschews a focus on
2018-10-24
Community capacity building eschews a focus on deficits and considers concepts of place through residents’ sense of GW788388 Supplier (Jung & Viswanath, 2013), and perceived collective efficacy. Consistent with Ellaway et al.’s (2001) findings that perceived problems within a community were associat
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Women who want to pursue
2018-10-24
Women who want to pursue a monogamous relationship are often prepared to forego genetic quality for some other attribute which favours a long-term relationship (e.g., status, ambition, generosity) and indicates an ability and disposition to devote long-term resources to the woman and to children (Ke
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br Limitations and future lines of
2018-10-24
Limitations and future lines of investigation This exploratory study has a series of limitations. First, the use of a sample of university students from a specific school can affect the external validity of the results. Second, we studied parental influence in only one region of Spain. Thus, a co
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br Acknowledgement br Introduction In the
2018-10-24
Acknowledgement Introduction In the past few decades, research and engineering interest has been focused toward lignocellulosic fibers such as flax, hemp, sisal and date palm due to their several economical, technical and environmental advantages (Mwaikambo and Ansell, 2002; Bernard et al., 2
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br Problem solved By the
2018-10-23
Problem solved By the time Wicksell wrote his 1900 article on marginal productivity and volume 1 of his Lectures (preface dated February 1901), it became clear that the main issue involving the machinery question was not empirical, but theoretical. If correct, the notion that a viable technical c
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