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br Proposed method of restoration The chronology table Table
2018-11-14
Proposed method of restoration The chronology table (Table 1) shows that numerous attempts to restore Rumeli Hisarı were undertaken. The restoration strategy for the castle should include an initial assessment of these attempts. Ayverdi and Gabriel conducted extensive building surveys on Rumeli H
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br Experimental Procedures br Acknowledgments We would like
2018-11-14
Experimental Procedures Acknowledgments We would like to thank Dr. J.C. Louis (Amgen) for the CG4 cell line (Louis et al., 1992), Dr. J. Trotter (University of Mainz) for the Oli-neu cell line (Jung et al., 1995), J. Hightower for artwork, and Dr. M. Götz and members of the O.H. lab for valuab
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The Douay group reported that when
2018-11-14
The Douay group reported that when adult HSC-derived mature erythroblasts were peripherally injected into the donor, at least half could survive in circulation for as long as 26 days (Giarratana et al., 2011). However, these in vitro expanded mature erythroblasts did not accumulate in a specific org
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br Methods br Results br Discussion Peritoneal micro metasta
2018-11-14
Methods Results Discussion Peritoneal micro-metastases are a common occurrence and portend poor prognosis for many malignancies including ovarian, gastric, and pancreatic cancer (Ferrone et al., 2006; Merchant et al., 1999; Bentrem et al., 2005; Burke et al., 1998; Yachida et al., 2002; Yos
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Androgen signaling is central to prostate cancer
2018-11-14
Androgen signaling is central to prostate cancer development and progression. A milestone in progression of advanced prostate cancer when it transitions from endocrine-driven to paracrine- or intracrine-driven androgen signaling, with progressive complexities in steroid hormone biosynthesis and alte
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br Relationship of Fatty Liver with the Metabolic Syndrome T
2018-11-14
Relationship of Fatty Liver with the Metabolic Syndrome Traditionally deemed to be the “hepatic manifestation of the metabolic syndrome”, NAFLD is more correctly deemed to be bi-directionally linked with either the Metabolic Syndrome (MetS) or its individual components. Indeed, on the one hand me
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In a historic referendum on June the
2018-11-14
In a historic referendum on June 23, 2016, the UK voted to leave the European Union (EU) after more than four decades of membership. For the time being, the UK is still a member of the EU until the UK government triggers Article 50 of the Lisbon Treaty–which probably won\'t happen before the end of
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Thus age maturation affects speed of isoniazid acetylation b
2018-11-14
Thus, age (maturation) affects speed of isoniazid acetylation by modifying effect of genotype, a non-linear interaction, however after 5.3years the maturation is complete. Table 4 shows the BFs for NAT2 affinity for isoniazid, or Km. A child\'s height was the primary predictor and had the highest v
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The racial disparity in US rates of cancer among
2018-11-14
The racial disparity in US rates of cancer (among other diseases) has been well-characterized and continues to persist with African-Americans having generally worse cancer incidence and mortality than Whites (). While many researchers have identified proximal causes for this disparity current resear
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The rationale for use of FASN inhibitors as a key
2018-11-14
The rationale for use of FASN inhibitors as a key component of combination therapy derives from known cellular effects of FASN inhibition (Ventura et al., 2015; Chuang et al., 2011; Kridel, 2004; Puig et al., 2009, 2008; Tomek et al., 2011) that include (1) blockade of palmitate synthesis, (2) disru
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Workflow Mascot Distiller Mascot Skyline
2018-11-14
Workflow 8: Mascot Distiller/Mascot/Skyline/MS Signal analysis. Peaklist creation was performed with Mascot Distiller as described in workflow 3, then database searches were performed with Mascot and validated with Scaffold as described for workflow 4. XIC signal corresponding to all validated pepti
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Previous evidences indicate that EDS
2018-11-13
Previous evidences indicate that EDS and SOS episodes have a different pattern of manifestation in PD. For instance, EDS is frequently found [7]; otherwise, SOS is less common and manifests somewhat similar to narcoleptic events [8]. Of note, the extent and severity of SOS in PD is variable: some pa
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During summers and winters in Antarctica the most extreme an
2018-11-13
During summers and winters in Antarctica, the most extreme and isolated continent on earth, the human circadian clock cannot rely on changes of photoperiod and temperature to entrain the clock day after day, and circadian rhythms might tend to free run [17]. Sleep disorders reported in Antarctic cre
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The contemporary physicians have more knowledge
2018-11-13
The contemporary physicians have more knowledge about this condition, and in the diagnosis and in therapeutic choices, given that the treatment should be individualized for each patient. The high costs of the treatments, the lack of therapeutic adherence as well as inadequate compliance of the patie
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br Materials and methods br Results and discussion
2018-11-13
Materials and methods Results and discussion Conclusion Our previous publications have established a five month-long stable C-FBN-C on a microelectrical array as a C-FBN-biosensor [10,11] and characterized it pharmacologically by investigating its responsiveness to Mg, TTX, and VER ([12], i
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