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Numerous clinical trials phase II and phase III
2019-05-28
Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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Close inspection of the tumor matrix on the initial
2019-05-28
Close inspection of the tumor matrix on the initial and subsequent 5 month radiographs (Fig. 7), shows an atypical appearance for osteoid matrix that ctap may more closely resemble chondroid matrix. The matrix appears to display a linear dense lace-like pattern (Fig. 8). Of the only two other cases
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br Conclusion Our findings may help physicians in selecting
2019-05-28
Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic galanin is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it may
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The benign exostoses in TRPS have a
2019-05-28
The benign exostoses in TRPS have a recognized malignant potential which have been shown to develop into chondrosarcomas [4,13]. Both our index case and his mother demonstrated de novo high grade osteosarcoma. To our knowledge, this occurrence has not been described anywhere within the literature.
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br Conflict of interest statement br Acknowledgments
2019-05-28
Conflict of interest statement Acknowledgments Funded by the Division of Medical Oncology at Princess Margaret Hospital, Toronto, Canada. No pharmaceutical company funding was received. The authors acknowledge the roles of Esther Lee and Tazmin Usmani in trial coordination and Dr. Ranjeeta Mal
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br Material and methods br Results br Discussion In our
2019-05-28
Material and methods Results Discussion In our series, fracture progression was noted in 53% of the lesions and 5 patients presented with new fractures after RT. Previous studies reported on the rate of pathologic fractures after single or multifraction RT; however, they did not stratify be
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br Discussion False tendons are
2019-05-28
Discussion False tendons are usually benign, intraventricular myocardial structures, which may cause a musical murmur [1], rate-dependent ventricular extrasystoles, functional mitral regurgitation, or deformation of the LV cavity due to mechanical stretch and dilatation of the LV wall [1,2]. Fals
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br Conflict of interest br
2019-05-28
Conflict of interest Acknowledgments This study was supported by the National Natural Science Foundation of China (Nos. 81273501 and 81470378). Introduction Sudden cardiac death (SCD) is a tragic event and the aftermath is devastating to the surviving family and community. SCD occurs in ne
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La descripci n arquitect nica de la
2019-05-28
La descripción arquitectónica de la quinta es heterogénea, extensa, precisa, sugerente, sin duda uno de los pasajes en El fistol del diablo más revisados y pulidos por Payno, con la totalidad de la novela en mente, por lo tanto pleno de simbolismo histórico-cultural y de presagios. Por principio, el
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br Discussion The mechanism of
2019-05-27
Discussion The mechanism of verapamil-sensitive ILVT has been suggested as re-entry with an excitable gap and a slow conduction, because the VT can be induced, entrained, and terminated by programmed ventricular or atrial stimulation [1–6]. In addition, previous studies have suggested that the re
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br de Hern n Lara Zavala se suma
2019-05-27
de Hernán Lara Zavala se suma al acervo literario de novelas históricas de México. En los albores del México independiente, la novela histórica representó una vía de exploración y defini-ción del “ser nacional”. A casi dos siglos de distancia la novela histórica ocupa un lugar central en la produc
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tamoxifen citrate Supplier Como ha destacado Leonardo Tarife
2019-05-27
Como ha destacado Leonardo Tarifeño, “su obra nace de un malestar con el mundo que se estetiza para revelarse, y en ningún caso para ocultarse o refinarse” (75). Este malestar, aunado al afán realista localizable en su trabajo produce una búsqueda de elementos para acercar al lector con diversas fac
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metalloproteinase Article of the Universal Declaration
2019-05-27
Article 25 of the Universal Declaration of Human Rights states that “everyone has the right to a standard of living adequate for the health and well-being of himself and of his family, including food, clothing, housing and medical care and necessary social services, and the right to security in the
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STF-62247 manufacturer Las formas transmisibles no del sabe
2019-05-27
“Las formas transmisibles, no del saber o de la sabiduría de un hombre, sino sobre todo su vida vivida —y esa es la materia con que se hacen historias— sólo son adquiridas al morir”, afirma Walter Benjamin. La muerte atraviesa toda la Historia verdadera: como motivo, como temor, como asombro o recue
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Como se puede advertir en la
2019-05-27
Como se puede advertir en la narración de Cuadra o, más claramente, en la encuesta que elaboró Téfel, hay toda una toma de conciencia en los sectores medios e intelectuales respecto crth2 antagonist los pobres. Esta nueva conciencia proyectó también la necesidad de integrar la racionalidad nacional
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